Basaloid Squamous Cell Carcinoma at the Floor of the Mouth and Mandible: A Case Report
이준상, 김욱규, 황대석, 이준호, 최홍석, 최나래, 유미현, 김규천,
소속 상세정보
이준상 ( Lee Jun-Sang ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
김욱규 ( Kim Uk-Kyu ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
황대석 ( Hwang Dae-Seok ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
이준호 ( Lee Jun-Ho ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
최홍석 ( Choi Hong-Seok ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
최나래 ( Choi Na-Rae ) - Pusan National University School of Dentistry Department of Oral and Maxillofacial Surgery
유미현 ( Ryu Mi-Heon ) - Pusan National University School of Dentistry Department of Oral Pathology
김규천 ( Kim Gyoo-Cheon ) - Pusan National University School of Dentistry Department of Oral Anatomy
Abstract
Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of squamous cell carcinoma arising in various anatomical sites. This article describes a case history of BSCC of the floor of mouth with mandibular involvement, and further discusses the appropriate management of such case with reference to the literature review. A 52-year-old male patient was referred to our clinic from another university hospital. Segmental mandibulectomy with supraomohyoid neck dissection and mandible reconstruction with left fibular free flap under general anesthesia was performed, followed by radiotherapy. Histopathological examination on the tumor lesion revealed features of squamous cell carcinoma with comedo-type necrosis. A diagnosis of BSCC was given by the oral pathology specialist. Basaloid squamous cell carcinoma (BSCC) is a biphasic variant of SCC with both basaloid and squamous cell histology. A recent report showed that there is no significant difference in the prognosis. Due to the lack of accumulated research, close follow-up and continuous research are deemed necessary. Treatment that focuses on the stage of the tumor is appropriate. A periodic follow-up observation is also very important due to the occurrence of distant metastasis to the lungs.
키워드
Basaloid squamous cell carcinoma; Segmental mandibulectomy; Fibular free flap
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